Useful Links & Tools
- MSDS
- Certificate of Analysis
- 91590C Product Information (59 KB )
- The Science, Features and Benefits of LONG®R3IGF-I - SAFC Biosciences Technical Bulletin (147 KB )
- Frequently Asked Questions - Strategic Sourcing - SAFC Biosciences Technical Bulletin (56 KB )
- LONGR3IGF-I Frequently Asked Questions (47 KB )
91590C
Sigma
LONG®R3 IGF-I human
liquid, recombinant, expressed in Escherichia coli
Description
| Application | LONG R3 IGF-I is a recombinant analog of human insulin-like growth factor-I (IGF-I) that has been specifically engineered for the enhancement of cell culture performance. It is more biologically potent in vitro than either insulin or native IGF-I and has been shown to significantly increase recombinant protein production. It is ideal for both research and large-scale culture systems utilizing serum-free or low-level serum applications. All cells that have a growth response to insulin in cell culture have the potential to respond to LONG R3 IGF-I. LONG R3 IGF-I is effective in commercially relevant cell types including CHO, PER.C6™ and HEK 293. Hybridomas and fibroblasts have also been shown to respond to LONG R3 IGF-I. LONG R3 IGF-I is produced in a patented E. coli expression system without the use of animal-derived components. |
| LONG R3 IGF-I is a recombinant analog of human insulin-like growth factor-I (IGF-I) that has been specifically engineered for the enhancement of cell culture performance. It is more biologically potent in vitro than either insulin or native IGF-I and has been shown to significantly increase recombinant protein production. It is ideal for both research and large-scale culture systems utilizing serum-free or low-level serum applications. All cells that have a growth response to insulin in cell culture have the potential to respond to LONG R3 IGF-I. LONG R3 IGF-I is effective in commercially relevant cell types including CHO, PER.C6® and HEK 293. Hybridomas and fibroblasts have also been shown to respond to LONG R3 IGF-I. LONG R3 IGF-I is produced in a patented E. coli expression system without the use of animal-derived components. | |
| Legal Information | LONG is a registered trademark of Novozymes Biopharma AU |
| PER.C6 is a registered trademark of Crucell N.V. |
Properties
| recombinant | expressed in Escherichia coli |
| form | liquid |
| concentration | 1 mg/mL in 0.1 M acetic acid |
